123I-ADAM SPECT imaging of serotonin transporter binding in patients with Night Eating Syndrome: A preliminary report
نویسندگان
چکیده
منابع مشابه
123I-ADAM SPET imaging of serotonin transporter in patients with epilepsy and comorbid depression
BACKGROUND Purpose of the study was to investigate alterations in midbrain serotonin transporter (SERT) binding in patients with epilepsy and symptoms of depression compared to patients with epilepsy with no symptoms of depression. METHODS We studied 12 patients with epilepsy (7 patients had focal and 5 had generalized epilepsy syndromes). The presence of self-reported symptoms of depression ...
متن کاملEvaluation of the Serotonin Transporter Ligand 123I-ADAM for SPECT Studies on Humans.
UNLABELLED Imaging serotonin transporters in the living human brain is important in several fields, such as normal psychophysiology, mood disorders, eating disorders, and neurodegenerative disorders. The aim of this study was to compare different kinetic and semiquantitative methods for assessing serotonin transporters using (123)I-labeled 2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenyla...
متن کاملCentral serotonin transporter availability measured with [123I]beta-CIT SPECT in relation to serotonin transporter genotype.
OBJECTIVE A functional polymorphism has been described in the promoter region of the gene (SLC6A4) coding for the serotonin transporter protein (SERT). This polymorphism has two common alleles, designated as long and short. Each allele has been linked with a number of human clinical phenotypes, including neuropsychiatric diseases associated with dysregulation of serotonin transmission. In vitro...
متن کامل123I-ADAM binding to serotonin transporters in patients with major depression and healthy controls: a preliminary study.
UNLABELLED The serotonergic system may play an important role in the pathophysiology of major depressive disorder (MDD). Few imaging studies have examined serotonin transporter (SERT) binding in patients with MDD. We hypothesized that SERT binding activity may be altered in patients with MDD. This study compared SERT binding in patients with MDD with that in healthy controls. METHODS We studi...
متن کاملI-ADAM SPECT in Healthy Nonhuman Primates: A Preliminary Report
Received 1/9/2002; revised 2/27/2002; accepted 3/6/2002. For correspondence or reprints contact: Wen-Sheng Huang, M.D., Department of Nuclear Medicine, Tri-Service General Hospital, 325 Section 2, Cheng-Kung Road, Taipei 114, Taiwan, R.O.C. Tel: (886)2-87927374, Fax: (886)2-87927217, E-mail: [email protected] Background: Serotonin transporter (SERT) plays a major role in modulating seroto...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Psychiatry Research: Neuroimaging
سال: 2008
ISSN: 0925-4927
DOI: 10.1016/j.pscychresns.2007.07.006